What is DYPHOX?
Dyphox® is a simple and effective disinfection method – a process that has been taken from nature. Dyphox® uses light in the visible wavelength range to activate the available oxygen, e.g. from the ambient air. No toxic biocides or metals such as silver are used to make Dyphox® effective.
Which germs does DYPHOX work against?
Dyphox® has a broad spectrum of effectiveness against different types of bacteria (e.g. Staphylococcus aureus or Escherichia coli), enveloped and non-enveloped viruses and fungi (e.g. Aspergillus niger or Candida albicans). Dyphox® also reliably inactivates multi-resistant germs.
Does DYPHOX require special light?
Dyphox® works with visible light (natural or artificial light) and requires no UV or infrared radiation.
Is the effectiveness of DYPHOX affected by environmental conditions?
No. Dyphox® works reliably on dry and damp surfaces. Even at extreme temperatures (>45°C in the shade or temperatures <0°C), the antimicrobial effectiveness is not impaired.
How much light is necessary?
Dyphox® works in normal room light, such as a ceiling light with a standard fluorescent tube or even LEDs.
Which component of DYPHOX is antimicrobial?
The singlet oxygen produced locally provides the antimicrobial effect.
What is singlet oxygen?
The Dyphox® photocatalysts continuously transfer the energy of the existing light to the oxygen molecules in the direct environment, putting them into an excited state. The scientific term for this oxygen activated by Dyphox® is called singlet oxygen. It can react particularly easily with the envelope of micro-organisms, thus killing them. The excited state is only maintained for a brief period before the oxygen returns to its natural state. On the one hand, this ensures that the germicidal effect only takes place in the immediate vicinity of the photocatalyst (e.g. on surfaces treated with Dyphox® Universal). On the other hand, accumulation in the air we breathe (as is the case with ozone disinfection, for example) is ruled out, thus eliminating any risk to humans and animals.
Is the singlet oxygen a concern?
No, singlet oxygen is completely safe for humans and animals. Dyphox® forms an extremely thin membrane of singlet oxygen, which is only active in very close proximity to the coating.
Where is DYPHOX Universal in use today?
The Dyphox® Universal coating has been extensively tested and has proven its effectiveness at two German clinics over several months, including in the emergency room. Today, Dyphox® Universal is used as a treatment in clinics as well as offices and production facilities of various companies.
Are there official certificates verifying the antibacterial and antiviral effectiveness of DYPHOX Universal?
Yes. Antibacterial effectiveness of more than 99.99% germ reduction according to ISO 22196 (mod.) was demonstrated by the testing laboratory Quality Labs GmbH.
The antiviral effectiveness of the Dyphox® Universal coating with more than 99.98% reduction of infectious particles (enveloped viruses) according to ISO 21702 (mod.) has been confirmed by the certified virological testing laboratory Eurovir® Hygiene Labor GmbH.
Does DYPHOX Universal work against SARS-CoV-2?
SARS-CoV-2 belongs to the Coronaviridae virus family and is an enveloped virus. The Dyphox® Universal coating has been successfully tested against enveloped viruses.
Is DYPHOX Universal approved as a biocidal product?
The Dyphox® Universal coating is regulated as a “treated article”. Therefore, the coating solution itself must be listed as a biocidal product or authorisation must be obtained in accordance with the European Biocidal Products Regulation (Regulation (EU) No. 528/2012). This is expected around 2023-24. Currently, a transitional period according to Article 93 of the European biocide regulation is in effect, since the related active substance dossier “Reactive Oxygen Species from ambient air or water” is still under review by ECHA.
Which additional documents does TriOptoTec GmbH provide for DYPHOX Universal?
Technical data sheets, mixing instructions, batch control documents and certificates of conformity are available for the Dyphox® Universal coating.
Does DYPHOX Universal replace surface disinfection?
We recommend the Dyphox® Universal coating as an additional hygiene measure to keep the germ load between disinfection cycles as low as possible. We cannot and do not want to replace manual surface disinfection and hand disinfection. Instead, we understand effective hygiene as a combination of various measures.
Is it possible to provide individual proof of effectiveness in field trials for my specific application of DYPHOX Universal?
Individual proof of effectiveness in field trials is very complex and costly, and therefore only possible at great expense. In order to make a statistically valid statement, a large number of samples must be taken and evaluated over a long period of time (several months). In addition, suitable control surfaces must be defined in order to have a reference point. It must also be ensured that the samples taken always reach the laboratory for analysis within 1–2 hours. This is an immense logistical challenge, especially for non-stationary objects.
We have already conducted a field study of this type at two hospitals. Over 9 months, nearly 1300 samples were taken and evaluated. As a result, we were able to make a reliable statement on the effectiveness under real conditions. Just one or only a few swabs only provide “snapshots” and cannot be used to make any reliable statement about the effectiveness of the coating.
Where is DYPHOX used as an additive today?
In cooperation with partners from the paint, printing varnish and wall paint industries, products containing Dyphox® additives have already been successfully launched on the market.
How is the antimicrobial effectiveness proven for products containing DYPHOX as an additive?
The proof is provided individually, in cooperation with you and independent testing laboratories.
How are products considered under the European biocide regulation when they are treated with DYPHOX as an additive? What obligations arise from this?
From a regulatory perspective, once a product is equipped with the respective additive, a biocidal product is created. This product must be approved by the manufacturer and distributor in accordance with the provisions of the European biocide regulation (Regulation (EU) No. 528/2012) for the respective area of application. The rules for treated products (Article 58 of Regulation (EU) No 528/2012) also apply.